IAMGSD REPORTS

The following reports and papers have been produced by IamGSD and it’s board members. 
NUTRITIONAL KETOSIS IN MCARDLE DISEASE: A SITUATION REPORT

IAMGSD, 2018

This statement is intended to assist clinicians and researchers by providing an insight into the knowledge gained from patients’ own testing and development of nutritional ketosis. This may inform formal research and help to speed the path to an eventual clarification ofwhether this is a suitable nutritional strategy for many McArdle patients.

CAN A LOW-CARBOHYDRATE DIET IMPROVE EXERCISE TOLERANCE IN MCARDLE DISEASE?

iMed Journals, 2017

Reason SL, Westman EC, Godfrey R and Maguire E

Journal of Rare Disorders: Diagnosis & Therapy ISSN 2380-7245, 2017, Vol. 3 No. 1: 1

We report the novel experience of three patients with McArdle disease that have adopted a Low-Carbohydrate Ketogenic Diet (LCKD) to manage their exercise intolerance. In each case, a distinct improvement in activity and exercise tolerance was found. Plasma Creatine Kinase (CK) was significantly lowered in all three cases, with two patients exhibiting values within normal range. Overall, each patient described an improved quality of life.

Conclusion: A carbohydrate-restricted diet may provide patients with McArdle disease with a consistent energy substrate for working muscles, thereby reducing the risk of muscle damage and threat of renal failure. Further research on the use of a LCKD in McArdle disease is warranted.

What is IamGSD?

We are a patient-led international group encouraging efforts by research and medical professionals, national support groups and individual patients worldwide.

What is Muscle GSD?

Human bodies make glucose from carbohydrates. Excess glucose is stored as glycogen in our muscles and liver. Muscle glycogen storage disease is when our muscles cannot convert their glycogen back into glucose to power our muscles.

Muscle GSDs links
If you have another muscle GSD please contact us.

Site updated: 07/2020.

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